Studies on the Effect of Oxidative Stress on Glaucoma
Keywords:
Effect, oxidative stress, glaucomaAbstract
A Cross Sectional study to evaluate the levels of Vitamin A,Vitamin C, Vitamin E, GPX, SOD, and MDA in cataract attending clinic at Federal Teaching Hospital, Owerri was carried out. A total of subjects comprising 250 cataract patients and control and within the ages of 25 and 70 years were recruited for the study.. All kits were commercially purchased and the manufacturer’s standard operational procedures were strictly followed. Data was analyzed using the software statistical package for social sciences version 21, windows 9, values were expressed as mean standard deviation, student t-test and analysis of variance were used to analyze the difference in experimental variables, Results showed that there were significant lower levels of Vitamin A (3.30±0.83mg/dl), Vitamin C(30.96±5.54 mg/dl), Vitamin E (8.99±1.49 mg/dl), (5.46±1.15, 44.35±6.40, 13.95±3.86) respectively (p<0.05). There was a significant decrease in MDA compared with the control p<0.05).
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